AIDS Research and Therapy

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Open Access Case report

Immune reconstitution syndrome presenting as probable AIDS-related lymphoma: a case report

Bo K Mortensen1,2, Susanne D Nielsen1, Charlotte B Christensen3 and Jannik Helweg-Larsen1*

Author Affiliations

1 Department of Infectious Diseases, Rigshospitalet, Copenhagen, Denmark

2 Department of Hematology, Rigshospitalet, Copenhagen, Denmark

3 Department of PET/CT imaging, Rigshospitalet, Copenhagen Denmark

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AIDS Research and Therapy 2011, 8:34 doi:10.1186/1742-6405-8-34

Published: 28 September 2011

Abstract

We report an unusual case of HIV-related immune reconstitution inflammatory syndrome, presenting as suspected AIDS-related lymphoma. Symptoms, initial investigations including fine-needle biopsy and 18F-FDG PET/CT scan were highly compatible with high grade AIDS-related lymphoma, however subsequently IRIS was diagnosed. We discuss pitfalls in the interpretation of diagnostic results in ARL versus IRIS.

Keywords:
Immune reconstitution inflammatory syndrome; AIDS related lymphoma; Cart; HIV; 18F-FDG PET/CT