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HIV post exposure prophylaxis induced bicytopenia: a case report

Benjamin T Schleenvoigt13*, John P Fobiwe1, Peter M Keller13, Stefan Hagel124 and Mathias W Pletz14

Author Affiliations

1 Center for Infectious Diseases and Infection Control, Jena University Hospital, Erlanger Allee 101, Jena, Thuringia 07740, Germany

2 Department of Internal Medicine IV, Jena University Hospital, Jena, Germany

3 Institute for Medical Microbiology, Jena University Hospital, Jena, Germany

4 Center for Sepsis Control and Care (CSCC), Jena University Hospital, Jena, Germany

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AIDS Research and Therapy 2014, 11:11  doi:10.1186/1742-6405-11-11

Published: 7 February 2014


Long and short term side effects of antiretroviral drugs are not fully understood yet. Here a case of reversible blood count changes following post exposure prophylaxis with tenofovir/emtricitabin and lopinavir/ritonavir is reported. We propose that antiretroviral drugs used in post exposure prophylaxis may have a significant impact on hematopoiesis.

HIV; Post exposure prophylaxis; Leukopenia; Thrombocytopenia; Tenofovir; Emtricitabin; Lopinavir; Ritonavir